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Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets)
Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets)
Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) is a combination of lamivudine and zidovudine, which belong to the nucleoside analog class of antiretroviral drugs. Each tablet of Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) contains half of the commonly prescribed daily doses of both lamivudine and zidovudine. With the availability of this combination tablet, patients may be better able to adhere to complex drug treatment regimens, thereby enhancing compliance.
What is Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) used for?
Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) are prescribed to treat HIV infection in patients with or without acquired immunodeficiency syndrome (AIDS). HIV directly affects the immune system by impairing the specific immune cells (CD4) that counter infection, so the risk of life-threatening infection increases. Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) medicine can prevent or slow down the ability of HIV to replicate, lowering the capacity of the virus. This medication functions to increase the number of CD4 cells, providing good strength to the immune system and defying the risk of disease.
How does Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) work?
Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) contain a combination of two antiretroviral drugs lamivudine and zidovudine, which both belong to class of drugs known as nucleoside analogue reverse transcriptase inhibitors (NRTI) that are only effective against retroviruses (RNA virus) like HIV. A nucleoside is a building block of DNA that is needed by the virus to replicate, and nucleoside analogues, like lamivudine and zidovudine in Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets), become incorporated into the DNA that is copied from the virus RNA by an enzyme called reverse transcriptase. This blocks the action of reverse transcriptase and terminates the viral DNA chain so that it cannot become integrated into the DNA of the infected immune cell, which means that no more HIV can be produced. Lamivudine is highly synergistic with zidovudine, which means that it increases the effectiveness of zidovudine so that the combination of these two antiretroviral drugs in Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) slow down the replication of HIV within your body but cannot prevent the spread of the infection to others.
Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) Dosage and Administration
Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) contain 150mg of lamivudine and 300mg of zidovudine. The other variety available, Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) also contains 150mg of lamivudine and 300mg of zidovudine, as well as 200mg of nevirapine. Your physician will decide the required daily dosage and provide you with the necessary details related to the frequency of administration. It is essential that you fully comply with all directions given by your physician. Do not take more than the correct daily dosage, as this could put you at risk of serious health problems.
What does Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) contain?
Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) medicine has a combination of the active ingredients lamivudine (150mg) and zidovudine (300mg). Both of these are antiretroviral drugs that are used to treat HIV infection.
Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) Side effects
Patients undergoing antiretroviral treatment with Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) (Lamivudine/Zidovudine) should be aware that side effects are possible. These may include:
- Headaches
- A blocked nose
- Body fat movement
- Discomfort in the sinuses
- Insomnia or possible fatigue
The above mentioned side effects are usually considered mild, and patients should note that other reactions may also occur. Serious adverse events are generally less common. However, you must get to the hospital or consult a physician immediately if you notice aching of the muscles which does not go away, sores on the skin, soreness in the back that is severe, difficulty walking properly, tremors and any other severe side effects that have not been referenced here.
What medications interact with Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets)?
There is a list of medications that interact with Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) so, they should be avoided along with this drug. Some particular drugs that may react with Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) are anti-infective, pentamidine, amphotericin, flucytosine, vincristine, pyrimethamine, co-trimoxazole, the antiviral ganciclovir, dapsone, vinblastine and doxorubicin for cancer treatment. Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) should not be taken with some other agents like stavudine, emtricitabine, efavirenz, fosamprenavir, indinavir, ketoconazole, itraconazole, and probenecid.
Some other drugs that are affected by Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) include stavudine, the anticonvulsant phenytoin, and antiretroviral zalicitabine.
When Duovir Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) not be taken?
- One should avoid Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) in the conditions of:
- Allergic to lamivudine or zidovudine or any ingredients in Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets)
- Pregnancy or breastfeeding
- Abnormally low neutrophil counts
- Blood disorders such as anemia or bone marrow problems
- Kidney or liver disease
- Anxiety and sleeping problems
- Immune modulator interferon
How should Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) be taken?
Usually, you should take Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) as 1 tablet twice daily with a glass of water and with or without food. Your doctor can determine how much and how long this medicine should be taken. If you miss a dose of Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) then take it as soon as you remember, but don’t increase the amount to make up the missed dose.
Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) Precautions
Treatment of HIV with Duovir (Lamivudine 150mg and Zidovudine 300mg Tablets) cannot cure the virus. It will only help your body deal with and fight the infection. Therefore, it is essential that patients are aware of the risk posed to others who they may be in contact with. Take every necessary precaution to ensure that you do not infect anybody else with HIV.
Certain cases in which patients developed a severe and potentially life threatening disorder known as lactic acidosis have been reported. Ask your physician about the symptoms of this condition and get immediate medical help if you believe that you are affected by this condition.
- Availability: In Stock
- Model: Duovir
- Brand: Cipla